There are two types of vessels in the retina - arteries and veins. A retinal artery occlusion(RAO) is a blockage of one or many arteries/arterioles in the retina. This blockage can result from a clot blocking the vessel lumen or cholesterol lining the vessel wall and eventually blocking it. It can also be considered as a stroke (called by many as an ‘eye stroke’).. 

It is an ophthalmic emergency and needs urgent treatment.

Retinal artery occlusion

There are two types of vessels in the retina - arteries and veins. A retinal artery occlusion (RAO) is a blockage of one or many arteries/arterioles in the retina.

This blockage can result from a clot blocking the vessel lumen or cholesterol lining the vessel wall and eventually blocking it. It can also be considered as a stroke.


(called by many as an ‘eye stroke’).


It is an ophthalmic emergency and needs urgent treatment.

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Types of
Retinal Artery Occlusion

RAOs can be divided into two types depending on the type of vessel blocked.

  • Blockage of smaller arteries (arterioles) results in a Branch Retinal artery Occlusion (BRAO).

  • Occlusion of the major retinal artery I.e. central retinal artery results in Central Retinal Artery Occlusion (CRAO).

Risk factors of Retinal Artery Occlusion

Systemic risk factors include:

  • High blood pressure

  • Uncontrolled blood sugar

  • Elevated cholesterol

  • Smoking

  • Coronary artery disease

  • Carotid artery stenosis

  • Cardiac arrhythmias 

Other risk factors include:

  • Inflammation in the vessel walls

  • Coagulation disorders

  • Leukemias/Lymphomas

what are the Types of Retinal artery Occlusions?


RAOs can be divided into two types depending on the type of vessel blocked.

Blockage of smaller arteries (arterioles) results in a Branch Retinal artery Occlusion (BRAO).

Occlusion of the major retinal artery I.e. central retinal artery results in Central Retinal Artery Occlusion (CRAO).

Central Retinal Artery Occlusion (CRAO)

Branch Retinal artery Occlusion (BRAO)

Risk Factors for Retinal artery Occlusion

Systemic risk factors include:

  • High blood pressure

  • Uncontrolled blood sugar

  • Elevated cholesterol

  • Smoking

  • Coronary artery disease

  • Carotid artery stenosis

  • Cardiac arrhythmias

Other risk factors include:

  • Inflammation in the vessel walls

  • Coagulation disorders

  • Leukemias/Lymphomas

Retinal Artery Occlusion diagnosis

In case someone develops the above symptoms, they should contact an ophthalmologist immediately and avoid any delay in initiating treatment. Diagnosis involves: 


  • A good and thorough clinical examination including a dilated retina exam. A classical finding in CRAO is a “Cherry red spot” at the macula. 

  • Fundus fluoroscein angiography(FFA) to assess the circulation of the retina to check for signs of blockage and reduced retinal perfusion. 

  • Optical Coherence Tomography (OCT) shows swelling and thickening of the retinal layers in an acute occlusion. 

  •  Fundus Photograph: A picture of the retina may be taken to document the condition of the retina and it allows us to monitor the retina as well.

Other investigations including a full systemic workup and a cardiologist and/ or neurologist are also suggested.  Tests like ECG, Echocardiography, blood investigations, carotid doppler (ultrasound of the neck vessels) to rule out systemic risk factors. 

Draining fluid from the anterior chamber of the eye to induce hypotony - in order to dislodge any clot if present


  • If initiated early (within a few hours), there is a chance that the retinal perfusion may be restored to some extent. However the prognosis remains guarded as most patients do not reach a doctor early.

Treatment modalities include :

  • Lowering the eye pressure using IOP lowering drugs

  • Digital ocular massage

  • Draining fluid from the anterior chamber of the eye to induce hypotony - in order to dislodge any clot if present

  • Further treatment including vitrectomy has been tried in a few patients under guarded prognosis.

  • Hyperbaric oxygen therapy is being tried as a newer modality to help treat recent CRAO.

Your cardiologist or neurologist may start blood thinner and cholesterol lowering agents as well.

RAO is unpredicatable and no one can prevent its occurrence.


However, a good metabolic control of blood pressure, blood sugar and cholesterol goes a long way in preventing such serious conditions.

Avoidance of smoking is a major factor which is known to reduce the risk of RAO.

A healthy lifestyle, regular exercise and frequent follow ups are important ways by which one can maintain a healthy eyesight and long life.

In case someone develops the above symptoms, they should contact an ophthalmologist immediately and avoid any delay in initiating treatment. Diagnosis involves: 

Comprehensive dilated retina exam

A good and thorough clinical examination including a dilated retina exam. A classical finding in CRAO is a “Cherry red spot” at the macula.

Fundus fluoroscein angiography (FFA)

to assess the circulation of the retina to check for signs of blockage and reduced retinal perfusion.

Optical Coherence Tomography (OCT)

shows swelling and thickening of the retinal layers in an acute occlusion.

Fundus Photograph

A picture of the retina may be taken to document the condition of the retina and it allows us to monitor the retina as well.

Other investigations including a full systemic workup and a cardiologist and/ or neurologist are also suggested. Tests like ECG, Echocardiography, blood investigations, carotid doppler (ultrasound of the neck vessels) to rule out systemic risk factors. 

Treatment OF Retinal artery Occlusion

RAO is an emergency and needs immediate intervention.

If initiated early (within a few hours), there is a chance that the retinal perfusion may be restored to some extent.

However the prognosis remains guarded as most patients do not reach a doctor early. 


Treatment modalities include :

  • Lowering the eye pressure using IOP lowering drugs

  • Digital ocular massage 

  • Draining fluid from the anterior chamber of the eye to induce hypotony - in order to dislodge any clot if present

  • Further treatment including vitrectomy has been tried in a few patients under guarded prognosis.

  • Hyperbaric oxygen therapy is being tried as a newer modality to help treat recent CRAO.

Your cardiologist or neurologist may start blood thinner and cholesterol lowering agents as well.

Prevention of Retinal Artery Occlusion

RAO is unpredicatable and no one can prevent its occurrence.

  • However, a good metabolic control of blood pressure, blood sugar and cholesterol goes a long way in preventing such serious conditions.

  • Avoidance of smoking is a major factor which is known to reduce the risk of RAO. 

  • A healthy lifestyle, regular exercise and frequent follow ups are important ways by which one can maintain a healthy eyesight and long life.

Frequently Asked Questions

Why does retinal vein occlusion affect eyesight?

The nerve cells of the retina convert light signals into electrical signals and transfer this to the brain to interpret.

These nerve cells need nutrients and oxygen to function- this is brought by the retinal artery. The metabolites and carbon dioxide are carried away by the retinal vein. 

Any blockage due to pressure from atherosclerosis (deposition of cholesterol and plaques inside vessels) in retinal artery or blood clots can cause retinal vein occlusion. 

When there is a blockage, the blood cells and the cells of the retinal vein walls release certain chemicals. These chemicals  produce edema and promote new blood vessels formation which affects eyesight by causing:

  • Macular Edema- The edema in the macula (the central most part of the retina responsible for fine vision)

  • Neovascularisation- proliferation of new, abnormal blood vessels on the retina. These new vessels are leaky and leak fluid and blood into the vitreous. This can lead to floaters, vitreous haemorrhage and even retinal detachment.

  • Neovascular glaucoma- rise in eye pressure due to new growth of blood vessels near the angle of the eye.

Blindness- If untreated, CRVO can cause irreversible blindness

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